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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZAP70
All Species:
11.21
Human Site:
Y319
Identified Species:
22.42
UniProt:
P43403
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43403
NP_001070.2
619
69872
Y319
T
S
V
Y
E
S
P
Y
S
D
P
E
E
L
K
Chimpanzee
Pan troglodytes
XP_515637
619
69840
Y319
T
S
V
Y
E
S
P
Y
S
D
P
E
E
L
K
Rhesus Macaque
Macaca mulatta
XP_001101570
619
69877
Y319
T
S
V
Y
E
S
P
Y
S
D
P
E
E
L
K
Dog
Lupus familis
XP_861301
601
68596
E323
S
P
Y
A
D
P
E
E
I
R
P
K
E
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
P43404
618
70040
S319
S
V
Y
E
S
P
Y
S
D
P
E
E
L
K
D
Rat
Rattus norvegicus
Q64725
629
71510
A323
P
Y
E
P
T
G
G
A
W
G
P
D
R
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515271
507
56102
G275
L
R
P
R
K
E
Q
G
T
Y
A
L
S
L
I
Chicken
Gallus gallus
Q07494
984
109166
Y531
Q
T
L
T
D
D
D
Y
K
S
E
L
R
E
Q
Frog
Xenopus laevis
Q91736
902
100832
L453
E
E
D
Y
K
S
E
L
R
E
Q
L
P
L
I
Zebra Danio
Brachydanio rerio
O13146
981
109636
E608
Y
I
H
P
H
T
Y
E
D
P
N
Q
A
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24145
939
104255
K635
M
A
S
Y
L
H
R
K
C
S
G
T
P
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189062
746
84636
Q367
V
A
Y
A
D
R
N
Q
R
R
I
A
S
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
53.6
N.A.
93.5
53.7
N.A.
57.6
22.6
24.2
25.2
N.A.
25.1
N.A.
N.A.
34
Protein Similarity:
100
100
98.3
70.4
N.A.
96.1
70.9
N.A.
62.6
35.5
39.1
37.4
N.A.
40.8
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
6.6
6.6
20
0
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
40
N.A.
13.3
13.3
N.A.
20
33.3
33.3
26.6
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
17
0
0
0
9
0
0
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
25
9
9
0
17
25
0
9
0
0
17
% D
% Glu:
9
9
9
9
25
9
17
17
0
9
17
34
34
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
9
9
0
9
9
0
0
9
0
% G
% His:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
9
0
9
0
0
0
17
% I
% Lys:
0
0
0
0
17
0
0
9
9
0
0
9
0
9
25
% K
% Leu:
9
0
9
0
9
0
0
9
0
0
0
25
9
42
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% N
% Pro:
9
9
9
17
0
17
25
0
0
17
42
0
17
0
0
% P
% Gln:
9
0
0
0
0
0
9
9
0
0
9
9
0
0
9
% Q
% Arg:
0
9
0
9
0
9
9
0
17
17
0
0
17
0
9
% R
% Ser:
17
25
9
0
9
34
0
9
25
17
0
0
17
9
0
% S
% Thr:
25
9
0
9
9
9
0
0
9
0
0
9
0
0
9
% T
% Val:
9
9
25
0
0
0
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
9
9
25
42
0
0
17
34
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _